Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.61 |
| ▸ | NOS3 | P29474 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 2/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL27355022 | 0.90 | NOS1 (0.50) | NOS1NOS3NOS2KCNK3KCNK9 | |
| SCHEMBL7081205 | 0.88 | NOS1 (0.66) | NOS1NOS3NOS2MAPTSMN1; SMN2 | |
| SCHEMBL9037289 | 0.88 | KCNK3 (0.67) | NOS1NOS3NOS2KCNK3KCNK9 | |
| SCHEMBL7080394 | 0.83 | SMN1; SMN2 (0.51) | NOS1KCNK3KCNK9SMN1; SMN2 | |
| SCHEMBL9046185 | 0.83 | NOS1 (0.58) | NOS1NOS3NOS2MAPTSMN1; SMN2 | |
| Bromide SCHEMBL7132671 | 0.82 | SMN1; SMN2 (0.50) | NOS1NOS3NOS2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7078869 | 0.82 | NOS3 (0.59) | NOS1NOS3NOS2MAPTSMN1; SMN2 | |
| SCHEMBL6961159 | 0.81 | NOS1 (0.59) | NOS1NOS3NOS2MAPT | |
| SCHEMBL7082364 | 0.81 | SMN1; SMN2 (0.61) | MAPTSMN1; SMN2 | |
| Oxalic Acid SCHEMBL27363239 | 0.80 | KCNK3 (0.58) | NOS1NOS3NOS2KCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071746-C | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 2001-09-26 | — | — | CN | claimed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | claimed |
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | claimed |
| EP-0713483-B1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRAZENECA AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| US-6030985-A | Amidine derivatives with nitric oxide synthetase activities | ASTRA AKTIEBOLAG (SE) | 2000-02-29 | — | — | US | disclosed |
| US-5807885-A | Amidine derivatives with nitric oxide synthetase activities | ASTRA AKTIEBOLAG (SE) | 1998-09-15 | — | — | US | disclosed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | disclosed |