Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | FPR1 | P21462 | 2/20 | 0.37 |
| ▸ | FPR2 | P25090 | 2/20 | 0.37 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 7/20 | 0.35 |
| ▸ | HAT1 | O14929 | 4/20 | 0.35 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7964635 | 0.84 | TP53 (0.47) | EP300HAT1GRM7MEN1USP2 | |
| SCHEMBL6977743 | 0.83 | PTGER4 (0.46) | PTGER4FPR1FPR2MEN1USP2 | |
| SCHEMBL6977399 | 0.81 | PTGER4 (0.42) | PTGER4FPR1FPR2MEN1USP2 | |
| SCHEMBL6983660 | 0.80 | PTGER4 (0.40) | PTGER4FPR1FPR2EP300GRM7 | |
| SCHEMBL6985248 | 0.79 | MAPT (0.42) | PTGER4FPR1FPR2MEN1USP2 | |
| SCHEMBL6980417 | 0.78 | PTGER4 (0.39) | PTGER4FPR1FPR2MEN1USP2 | |
| SCHEMBL6979727 | 0.77 | TSHR (0.40) | PTGER4FPR1FPR2MEN1USP2 | |
| SCHEMBL6981829 | 0.77 | POLB (0.39) | PTGER4FPR1FPR2MEN1USP2 | |
| SCHEMBL6985381 | 0.77 | MMP1 (0.45) | PTGER4FPR1FPR2KMT2A | |
| SCHEMBL6984361 | 0.76 | PTGER4 (0.39) | PTGER4FPR1FPR2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |