Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984787 | 0.89 | ATM (0.48) | ATMKMT2AHDAC1HDAC6RAB9A | |
| SCHEMBL6986817 | 0.88 | THRB (0.42) | ATMKMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL6977743 | 0.86 | PTGER4 (0.46) | NR3C1ARKMT2AHDAC1HDAC8 | |
| SCHEMBL6980994 | 0.86 | RXRA (0.43) | ATMKMT2AHDAC6PTGER4RAB9A | |
| SCHEMBL6986437 | 0.85 | PTGER4 (0.41) | ATMKMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL6984462 | 0.85 | ATM (0.41) | ATMKMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL6977399 | 0.84 | PTGER4 (0.42) | NR3C1ARKMT2APTGER4RAB9A | |
| SCHEMBL6977736 | 0.84 | CHRM3 (0.40) | ATMKMT2APTGER4RAB9AFPR1 | |
| SCHEMBL6985322 | 0.84 | GAA (0.41) | NR3C1ARKMT2AHDAC1HDAC8 | |
| SCHEMBL6985566 | 0.84 | PARP14 (0.40) | ATMNR3C1ARKMT2APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |