Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17309049 | 0.89 | ALDH1A1 (0.55) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL1042708 | 0.88 | HSPB1 (0.73) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL29390372 | 0.88 | HSPB1 (0.73) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL28221135 | 0.86 | ALDH1A1 (0.51) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL10548431 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL20328418 | 0.84 | TDP1 (0.66) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL20328412 | 0.84 | TDP1 (0.66) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL123957 | 0.84 | ALDH1A1 (0.61) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL10528527 | 0.84 | ALDH1A1 (0.57) | ALDH1A1GPR35MAPK1HPGDTP53 | |
| SCHEMBL397931 | 0.84 | TDP1 (0.66) | ALDH1A1GPR35MAPK1HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155940-A1 | DNP AND DNP PRODRUG TREATMENT OF NEUROMUSCULAR, NEURODEGENERATIVE, AUTOIMMUNE, DEVELOPMENTAL, CONCUSSION, DRY EYE DISEASE, AND/OR METABOLIC DISEASES | Mitochon Pharmaceuticals, LLC (US) | 2017-09-14 | — | — | WO | disclosed |
| US-8124443-B2 | Organic diodes and materials | MARROCCO MATTHEW L (US) | 2012-02-28 | — | — | US | disclosed |
| US-20100112751-A1 | ORGANIC DIODES AND MATERIALS | MARROCCO III MATTHEW L | 2010-05-06 | — | — | US | disclosed |
| US-7655961-B2 | Organic diodes and materials | MAXDEM INCORPORATED (US) | 2010-02-02 | — | — | US | disclosed |
| WO-2005034199-A2 | ORGANIC DIODES AND MATERIALS | MAXDEM INCORPORATED (US) | 2005-04-14 | — | — | WO | disclosed |
| US-20050072971-A1 | Organic diodes and materials | IPCO LLC | 2005-04-07 | — | — | US | disclosed |