Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6171653 | 1.00 | MEN1 (0.64) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL6172393 | 0.84 | MEN1 (0.69) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL7086102 | 0.84 | MEN1 (0.69) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL14559436 | 0.82 | MEN1 (0.43) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL5361050 | 0.82 | MEN1 (0.43) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL5361053 | 0.82 | MEN1 (0.43) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL6172072 | 0.79 | MAPT (0.74) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL7755244 | 0.76 | SMN1; SMN2 (0.50) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL7079886 | 0.76 | NPC1 (0.73) | MEN1TSHRKMT2AMAPTMAPK1 | |
| SCHEMBL7082776 | 0.74 | SMN1; SMN2 (0.59) | MEN1TSHRKMT2AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130125-A1 | Phenyl-substituted cyclic enaminones | FISCHER REINER (DE) | 2003-07-10 | — | — | US | disclosed |
| US-6455472-B1 | HERBICIDES, ACARICIDES, NEMATICIDES AND INSECTICIDES FOR CROPS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130125-A1 | Phenyl-substituted cyclic enaminones | DDT, CYP19A1, KCNA1 | MEN1 2817/4885TSHR 717/4885KMT2A 506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.