Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7755190 | 0.82 | HPGD (0.56) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL6172940 | 0.77 | NPC1 (0.67) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL7083412 | 0.77 | NPC1 (0.67) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL6171653 | 0.76 | MEN1 (0.64) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL7085153 | 0.76 | MEN1 (0.64) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL6112698 | 0.71 | PARP1 (0.55) | SMN1; SMN2KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL2345173 | 0.70 | CASP6 (0.58) | HPGDKMT2AMAPTMEN1TSHR | |
| SCHEMBL7086102 | 0.70 | MEN1 (0.69) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL7079886 | 0.69 | NPC1 (0.73) | SMN1; SMN2HPGDRAB9ANPC1KMT2A | |
| SCHEMBL6169261 | 0.69 | NPC1 (0.73) | SMN1; SMN2HPGDRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001060797-A1 | PHENYL-SUBSTITUTED HETEROCYCLIC ENAMINONES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-23 | — | — | WO | disclosed |