Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 11/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084239 | 0.93 | REN (0.48) | RENSLC6A5MCHR1KDM4EPKM | |
| SCHEMBL7082981 | 0.92 | REN (0.46) | REN | |
| SCHEMBL7079272 | 0.90 | REN (0.64) | RENSLC6A5 | |
| SCHEMBL7080647 | 0.90 | REN (0.48) | RENNR1H2 | |
| SCHEMBL7081646 | 0.90 | REN (0.50) | REN | |
| SCHEMBL7079555 | 0.87 | REN (0.63) | REN | |
| SCHEMBL7074027 | 0.86 | REN (0.45) | REN | |
| SCHEMBL7078232 | 0.86 | MAOA (0.46) | REN | |
| SCHEMBL7077230 | 0.86 | REN (0.45) | RENSLC6A5MCHR1KDM4E | |
| SCHEMBL7083199 | 0.86 | REN (0.46) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |