Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138764 | 0.87 | SMN1; SMN2 (0.41) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9138770 | 0.85 | LMNA (0.37) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL5973178 | 0.82 | LMNA (0.37) | LMNAKMT2A | |
| SCHEMBL7085491 | 0.82 | LMNA (0.37) | LMNAKMT2A | |
| SCHEMBL7085245 | 0.80 | LMNA (0.40) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7081235 | 0.78 | LMNA (0.44) | LMNAKMT2A | |
| SCHEMBL7103639 | 0.78 | — | — | |
| SCHEMBL9136104 | 0.77 | CA12 (0.39) | LMNAKMT2A | |
| SCHEMBL7080896 | 0.77 | POLB (0.43) | LMNAKMT2A | |
| SCHEMBL7085370 | 0.76 | MEN1 (0.43) | LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5384328-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0555351-B1 | OXYSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 1994-12-28 | — | — | EP | disclosed |
| US-5336690-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0592439-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5254715-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| US-5245068-A | Acylcoenzyme A cholesterol acyltransferase inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0555351-A1 | OXYSULFONYL CARBAMATES. | WARNER LAMBERT CO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992008693-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992007826-A1 | OXYSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |