Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7081235 | 0.87 | LMNA (0.44) | LMNAKMT2A | |
| SCHEMBL7080892 | 0.81 | LMNA (0.38) | POLBLMNAKMT2A | |
| SCHEMBL7615087 | 0.80 | HDAC1 (0.38) | POLBLMNAKMT2A | |
| SCHEMBL7617669 | 0.79 | MEN1 (0.39) | KMT2A | |
| SCHEMBL7081886 | 0.78 | LMNA (0.42) | LMNAKMT2A | |
| SCHEMBL7085130 | 0.77 | ALDH1A1 (0.48) | LMNAKMT2A | |
| SCHEMBL7085230 | 0.77 | LMNA (0.41) | LMNAKMT2A | |
| SCHEMBL7080899 | 0.77 | LMNA (0.47) | POLBLMNAKMT2A | |
| SCHEMBL7081976 | 0.77 | RBP4 (0.39) | — | |
| SCHEMBL7085245 | 0.77 | LMNA (0.40) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | claimed |
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5336690-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1994-08-09 | — | — | US | disclosed |
| US-5254715-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1993-10-19 | — | — | US | disclosed |