Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085756 | 0.83 | CA1 (0.45) | SMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL9139069 | 0.82 | CA2 (0.38) | ALDH1A1CA2 | |
| SCHEMBL9452033 | 0.80 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7082062 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL8754759 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7168915 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL7085257 | 0.76 | IDH1 (0.43) | CA2 | |
| SCHEMBL7082049 | 0.76 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL7085753 | 0.75 | ALDH1A1 (0.35) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7081888 | 0.75 | MEN1 (0.36) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592439-B1 | AMINOSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 2003-07-30 | — | — | EP | disclosed |
| US-5384328-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0555351-B1 | OXYSULFONYL CARBAMATES | WARNER LAMBERT CO (US) | 1994-12-28 | — | — | EP | disclosed |
| EP-0592439-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1994-04-20 | — | — | EP | disclosed |
| US-5254715-A | Anticholesterol agents | WARNER-LAMBERT COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| US-5245068-A | Acylcoenzyme A cholesterol acyltransferase inhibitors | WARNER-LAMBERT COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1992008693-A1 | AMINOSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992007826-A1 | OXYSULFONYL CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |