Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17407884 | 0.81 | NOS3 (0.41) | KDM4CNPY5RKCNH2CLK4 | |
| SCHEMBL7089309 | 0.81 | ASIC3 (0.52) | KDM4CASIC3KDM1A | |
| SCHEMBL22211412 | 0.79 | KDM4C (0.34) | KDM4CMAP3K14NPY5RKCNH2KDM1A | |
| SCHEMBL7085693 | 0.77 | KDM1A (0.45) | KCNH2KDM1AMAOA | |
| SCHEMBL9792784 | 0.76 | NPY5R (0.45) | KDM4CNPY5RKCNH2CLK4 | |
| SCHEMBL29500425 | 0.76 | NPY5R (0.45) | KDM4CNPY5RKCNH2CLK4 | |
| SCHEMBL7085687 | 0.75 | CCR1 (0.55) | KDM4CASIC3KDM1A | |
| SCHEMBL7088953 | 0.75 | KDM1A (0.43) | KDM4CMAP3K14ASIC3KDM1A | |
| SCHEMBL7089081 | 0.75 | IDO1 (0.42) | KDM4CASIC3KDM1ACDK2 | |
| SCHEMBL7088671 | 0.75 | KDM4C (0.49) | KDM4CASIC3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | claimed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | claimed |
| EP-1052252-B1 | Diaminobenzene derivatives and dyeing preparations containing them | WELLA AG (DE) | 2003-08-06 | — | — | EP | disclosed |
| US-6461388-B1 | Diaminobenzene derivative compounds and dye compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1052252-A1 | Diaminobenzene derivatives and dyeing preparations containing them | Wella Aktiengesellschaft (DE) | 2000-11-15 | — | — | EP | disclosed |