Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085734 | 1.00 | PTPN1 (0.44) | PTPN1PDPK1KMT2AMEN1L3MBTL1 | |
| SCHEMBL5787517 | 0.92 | KMT2A (0.45) | PTPN1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL5787511 | 0.92 | KMT2A (0.45) | PTPN1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL7080719 | 0.89 | PDPK1 (0.44) | PDPK1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL7080716 | 0.89 | PDPK1 (0.44) | PDPK1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL7081846 | 0.89 | PDPK1 (0.46) | PDPK1KMT2AMEN1ALDH1A1AKT1 | |
| SCHEMBL7081841 | 0.89 | PDPK1 (0.46) | PDPK1KMT2AMEN1ALDH1A1AKT1 | |
| SCHEMBL7082906 | 0.89 | PDPK1 (0.47) | PDPK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL7082903 | 0.89 | PDPK1 (0.47) | PDPK1KMT2AMEN1MAPTRAB9A | |
| SCHEMBL7089792 | 0.88 | RET (0.49) | PDPK1KMT2AMEN1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071665-B1 | SUBSTITUTED INDOLINONES HAVING AN INHIBITING EFFECT ON KINASES AND CYCLINE/CDK COMPLEXES | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-10-01 | — | — | EP | disclosed |
| US-6169106-B1 | ANTITUMOUR AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-01-02 | — | — | US | disclosed |