Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.65 |
| ▸ | GABRD | O14764 | 2/20 | 0.65 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.65 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.65 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.65 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.65 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.65 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.65 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.65 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.65 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.65 |
| ▸ | GABRE | P78334 | 2/20 | 0.65 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.65 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.65 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.65 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL27563645 | 0.93 | GABRP (0.65) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL1833787 | 0.90 | GABRP (0.62) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL542249 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL542250 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL542280 | 0.88 | GABRP (0.59) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL8397315 | 0.86 | EGLN1 (0.69) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Azelaic Acid SCHEMBL29465682 | 0.85 | TSHR (0.67) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Beta-Alanine SCHEMBL27717619 | 0.85 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Butyric Acid SCHEMBL21145057 | 0.85 | FFAR3 (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Succinic Acid SCHEMBL8062635 | 0.85 | GABRP (0.56) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103242944-B | Multifunctional water-based environment-friendly recyclable crystal silicon precision cutting liquid | SHANGHAI YEZONG PV TECHNOLOGY CO LTD | 2014-12-17 | — | — | CN | claimed |
| CN-103242944-A | Multifunctional water-based environment-friendly recyclable crystal silicon precision cutting liquid | SHANGHAI YEZONG PV TECHNOLOGY CO LTD | 2013-08-14 | — | — | CN | claimed |
| CN-108500511-A | The manufacturing method of flux composition, solder composition, electric substrate and electric substrate | 株式会社田村制作所 | 2018-09-07 | — | — | CN | disclosed |
| CN-103361644-B | For etching the fluid composition of the multilayer film comprising copper and molybdenum and using its engraving method | 三菱瓦斯化学株式会社 | 2017-08-04 | — | — | CN | disclosed |
| US-20160186057-A1 | ETCHING LIQUID COMPOSITION FOR MULTILAYER CONTAINING COPPER AND MOLYBDENUM AND PROCESS FOR ETCHING THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2016-06-30 | — | — | US | disclosed |
| CN-103242944-B | Multifunctional water-based environment-friendly recyclable crystal silicon precision cutting liquid | SHANGHAI YEZONG PV TECHNOLOGY CO LTD | 2014-12-17 | — | — | CN | disclosed |
| US-20140014615-A1 | ETCHING LIQUID COMPOSITION FOR MULTILAYER CONTAINING COPPER AND MOLYBDENUM AND PROCESS FOR ETCHING THEREOF | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-01-16 | — | — | US | disclosed |
| CN-103361644-A | A liquid composition for etching a multilayer film containing copper and molybdenum and an etching method using the same | MITSUBISHI GAS CHEMICAL CO | 2013-10-23 | — | — | CN | disclosed |
| CN-103242944-A | Multifunctional water-based environment-friendly recyclable crystal silicon precision cutting liquid | SHANGHAI YEZONG PV TECHNOLOGY CO LTD | 2013-08-14 | — | — | CN | disclosed |
| EP-1326824-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028815-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2002-04-11 | — | — | WO | disclosed |