Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 2/20 | 0.65 |
| ▸ | CDK1 | P06493 | 2/20 | 0.65 |
| ▸ | CDK4 | P11802 | 2/20 | 0.65 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.65 |
| ▸ | CCND1 | P24385 | 2/20 | 0.65 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | UBE2N | P61088 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702554 | 0.92 | APP (0.65) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL5702556 | 0.92 | APP (0.65) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4623828 | 0.92 | PDCD1 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL4623825 | 0.92 | PDCD1 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6735912 | 0.87 | CDK4 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7265006 | 0.87 | CDK4 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL6735911 | 0.87 | CDK4 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7264998 | 0.87 | CDK4 (0.60) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL7089735 | 0.85 | CCNB2 (0.63) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL29446267 | 0.84 | TACR2 (0.62) | LMNAKDM4EGSK3BAPPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4372976-A | TERTIARY-BUTYL (3,4-DIBENZYLOXY)STYRYL KETONE | STERLING DRUG INC. (US) | 1983-02-08 | — | — | US | claimed |
| US-6649784-B2 | Reductive alkylation of aspartame with aldehyde | AJINOMOTO CO., INC. (JP) | 2003-11-18 | — | — | US | disclosed |
| US-20030065210-A1 | Aspartyl dipeptide ester derivatives and sweeteners | AJINOMOTO CO. INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| US-4372976-A | TERTIARY-BUTYL (3,4-DIBENZYLOXY)STYRYL KETONE | STERLING DRUG INC. (US) | 1983-02-08 | — | — | US | disclosed |
| US-4372976-A | TERTIARY-BUTYL (3,4-DIBENZYLOXY)STYRYL KETONE | STERLING DRUG INC. (US) | 1983-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065210-A1 | Aspartyl dipeptide ester derivatives and sweeteners | DNPEP, DPP4, DPP3 | CCNB2 4728/4885CDK1 4153/4885CDK4 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.