Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.60 |
| ▸ | CCND1 | P24385 | 4/20 | 0.60 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.60 |
| ▸ | CDK1 | P06493 | 3/20 | 0.60 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.60 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6735911 | 1.00 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7265006 | 0.89 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7264998 | 0.89 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889922 | 0.87 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL5889923 | 0.87 | CDK4 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL7086040 | 0.87 | CCNB2 (0.65) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL980151 | 0.85 | MAOA (0.56) | FFAR4KDM4ELMNANPC1MAPT | |
| SCHEMBL27396127 | 0.85 | LCK (0.57) | FFAR4KDM4ELMNAAPPNPC1 | |
| SCHEMBL5702556 | 0.85 | APP (0.65) | CDK4CCND1CCNB2CDK1CCNB1 | |
| SCHEMBL4623828 | 0.85 | PDCD1 (0.60) | CDK4CCND1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6761922-B2 | MIXING AN ASPARTYL DIPEPTIDE ESTER COMPOUND OR SALT WITH A SOLID FILLER SELECTED FROM SUGAR, SUGAR ALCOHOL, OLIGOSACCHARIDE AND POLYSACCHARIDE | AJINOMOTO CO., INC. (JP) | 2004-07-13 | — | — | US | disclosed |
| US-20040105928-A1 | Sweetener compositions and uses thereof | AJINOMOTO CO. INC (JP) | 2004-06-03 | — | — | US | disclosed |
| US-6652901-B2 | Sweetener compositions and uses thereof | AJINOMOTO CO., INC. (JP) | 2003-11-25 | — | — | US | disclosed |
| US-6630191-B1 | Such as N-(N-(3-(3-hydroxy-4-methoxyphenyl)propyl)-L-alpha-aspartyl)-L -(alphamethyl)phenylalanine-1-methyl ester; stability; safety | AJINOMOTO CO., INC. (JP) | 2003-10-07 | — | — | US | disclosed |
| US-6548096-B1 | Aspartyl dipeptide ester derivatives and sweeteners | AJINOMOTO CO., INC. (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20030059511-A1 | Sweetener compositions and uses thereof | AJINOMOTO CO., INC. (JP) | 2003-03-27 | — | — | US | disclosed |
| US-20030044502-A1 | Sweetener compositions containing aspartyl dipeptide ester compounds | AJINOMOTO CO. INC (JP) | 2003-03-06 | — | — | US | disclosed |
| EP-1223175-A1 | SOLID SWEETENER COMPOSITIONS, LIQUID SWEETENER COMPOSITIONS AND UTILIZATION THEREOF | Ajinomoto Co., Inc. (JP) | 2002-07-17 | — | — | EP | disclosed |
| EP-1221448-A1 | SWEETENER COMPOSITIONS WITH HIGH DEGREE OF SWEETNESS HAVING IMPROVED SWEETNESS, CORRIGENTS AND UTILIZATION THEREOF | Ajinomoto Co., Inc. (JP) | 2002-07-10 | — | — | EP | disclosed |
| EP-1088829-A1 | NOVEL ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-1070726-A1 | ASPARTYL DIPEPTIDE ESTER DERIVATIVES AND SWEETENERS | Ajinomoto Co., Inc. (JP) | 2001-01-24 | — | — | EP | disclosed |