Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.37 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183245 | 0.87 | ALDH1A1 (0.42) | ALDH1A1THRATHRBMAPTCYP1A2 | |
| SCHEMBL28599247 | 0.87 | GRIK1 (0.44) | CA2ALDH1A1ALOX5THRATHRB | |
| SCHEMBL22551032 | 0.81 | MAPK1 (0.47) | CA2ALDH1A1ALOX5MAPTCYP1A2 | |
| SCHEMBL29793786 | 0.81 | EPHX2 (0.43) | EPHX2 | |
| SCHEMBL4828322 | 0.77 | MAPT (0.39) | ALDH1A1THRATHRBMAPTCYP1A2 | |
| SCHEMBL28058533 | 0.77 | CSNK1E (0.57) | — | |
| SCHEMBL22558568 | 0.77 | CSNK1E (0.57) | — | |
| SCHEMBL7789683 | 0.77 | CSNK1E (0.57) | — | |
| SCHEMBL28081007 | 0.77 | CSNK1E (0.57) | — | |
| SCHEMBL23870570 | 0.76 | MAPT (0.39) | ALDH1A1THRATHRBMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003075913-A1 | TOPICAL COMPOSTIONS COMPRISING FURFURYL DERIVATIVES AND THEIR USE FOR THE TREATMENT OF DERMATOLOGIC DISORDERS | GHISALBERTI CARLO (BR) | 2003-09-18 | — | — | WO | disclosed |