Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | PTGES | O14684 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22551032 | 0.94 | MAPK1 (0.47) | SLC1A2SLC1A1PTGESALOX5PPARG | |
| SCHEMBL29793786 | 0.92 | EPHX2 (0.43) | — | |
| SCHEMBL9183245 | 0.89 | ALDH1A1 (0.42) | ALDH1A1THRATHRB | |
| SCHEMBL1532410 | 0.88 | TDP1 (0.47) | GRIK1GRIK2SLC1A2SLC1A1MAPK1 | |
| SCHEMBL7086052 | 0.87 | CA2 (0.42) | GRIK1GRIK2ALOX5CA2ALDH1A1 | |
| SCHEMBL30505636 | 0.87 | ELANE (0.45) | SLC1A2SLC1A1PTGESALOX5PPARG | |
| SCHEMBL3931357 | 0.82 | NR4A2 (0.47) | SLC1A2SLC1A1ALOX5PPARGALDH1A1 | |
| SCHEMBL18339092 | 0.81 | NPC1 (0.42) | SLC1A2SLC1A1MAPK1ALDH1A1 | |
| SCHEMBL4828322 | 0.79 | MAPT (0.39) | ALDH1A1THRATHRB | |
| SCHEMBL23870570 | 0.77 | MAPT (0.39) | ALDH1A1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |