Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176763 | 0.71 | ALDH1A1 (0.40) | MEN1KMT2AALOX15 | |
| SCHEMBL5889044 | 0.62 | DAO (0.32) | — | |
| SCHEMBL4680572 | 0.61 | IKBKB (0.59) | MEN1CYP3A4KMT2ATDP1L3MBTL1 | |
| SCHEMBL11034047 | 0.61 | PTGDR (0.31) | — | |
| SCHEMBL28205570 | 0.60 | — | — | |
| SCHEMBL4970408 | 0.60 | DAO (0.45) | MEN1KMT2A | |
| SCHEMBL985212 | 0.59 | L3MBTL1 (0.54) | MEN1CYP3A4KMT2ATDP1L3MBTL1 | |
| SCHEMBL5026014 | 0.59 | PTGDR (0.34) | ALOX15 | |
| SCHEMBL1310694 | 0.59 | NPSR1 (0.49) | MEN1CYP3A4KMT2ATDP1L3MBTL1 | |
| SCHEMBL11151820 | 0.59 | KDM4E (0.38) | MEN1KMT2ATDP1L3MBTL1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214316-B1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INT LTD (CH) | 2003-05-07 | — | — | EP | disclosed |
| EP-1214316-A1 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD. (CH) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001016131-A2 | FIVE MEMBERED-RING COMPOUNDS AND UTILIZATION THEREOF IN LIQUID CRYSTAL MIXTURES | CLARIANT INTERNATIONAL LTD (CH) | 2001-03-08 | — | — | WO | disclosed |