Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088994 | 1.00 | HCAR2 (0.48) | HCAR2ATMMAPTTSHRCA12 | |
| SCHEMBL7644484 | 0.83 | HCAR2 (0.52) | HCAR2ATMMAPTTSHRNPSR1 | |
| SCHEMBL35468 | 0.83 | TSHR (0.59) | HCAR2MAPTTSHRLMNANPSR1 | |
| SCHEMBL28122801 | 0.79 | ALDH1A1 (0.50) | TSHRLMNAALDH1A1 | |
| SCHEMBL28629883 | 0.77 | ALDH1A1 (0.36) | HCAR2LMNAALDH1A1 | |
| SCHEMBL5662944 | 0.77 | ALDH1A1 (0.52) | MAPTTSHRLMNAALDH1A1RAB9A | |
| SCHEMBL1884148 | 0.77 | HCAR2 (0.42) | HCAR2ATMMAPTTSHRNPSR1 | |
| SCHEMBL1880535 | 0.77 | HCAR2 (0.42) | HCAR2ATMMAPTTSHRNPSR1 | |
| SCHEMBL297785 | 0.76 | MAPT (0.41) | ATMMAPTTSHRLMNAALDH1A1 | |
| SCHEMBL6276290 | 0.76 | MGAM (0.54) | ATMMAPTTSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331494-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS | NOF CORPORATION (JP) | 2003-07-30 | — | — | EP | disclosed |