SCHEMBL7086449

SCHEMBL7086449

CC(C)c1ccccc1N(C(=O)O)S(=O)(=O)N(c1ccccc1)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.39
TSHR P16473 1/20 0.36
ESR1 P03372 1/20 0.36
NR4A1 P22736 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7085480 0.86 POLB (0.40) LMNAPOLBTSHRKMT2A
SCHEMBL7085245 0.85 LMNA (0.40) LMNAALDH1A1TP53SMN1; SMN2KMT2A
SCHEMBL9423260 0.79
SCHEMBL7088353 0.79
SCHEMBL7085732 0.78 MEN1 (0.43) LMNAALDH1A1POLBTSHRKMT2A
SCHEMBL7080929 0.77
SCHEMBL9452028 0.77 CA1 (0.39) KMT2A
SCHEMBL7081220 0.75 LMNA (0.46) LMNAKMT2A
SCHEMBL9452038 0.75
SCHEMBL78109 0.75 SIGMAR1 (0.42) LMNAALDH1A1TP53SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0592439-B1 AMINOSULFONYL CARBAMATES WARNER LAMBERT CO (US) 2003-07-30 EP claimed