Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.50 |
| ▸ | HTR2C | P28335 | 9/20 | 0.50 |
| ▸ | MAOA | P21397 | 7/20 | 0.50 |
| ▸ | KDM1A | O60341 | 6/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086540 | 1.00 | MAOB (0.50) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL15254685 | 0.80 | KDM1A (0.53) | MAOBHTR2CMAOAKDM1ASLC6A2 | |
| SCHEMBL15254824 | 0.80 | KDM1A (0.53) | MAOBHTR2CMAOAKDM1ASLC6A2 | |
| SCHEMBL17781846 | 0.80 | KDM1A (0.53) | MAOBHTR2CMAOAKDM1ASLC6A2 | |
| SCHEMBL1786790 | 0.79 | SMN1; SMN2 (0.46) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL1786791 | 0.79 | SMN1; SMN2 (0.46) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL12611380 | 0.79 | SMN1; SMN2 (0.46) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL12611241 | 0.79 | SMN1; SMN2 (0.46) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL27991421 | 0.78 | MAOB (0.52) | MAOBHTR2CMAOAKDM1ACYP2C19 | |
| SCHEMBL9019856 | 0.76 | HTR2C (0.57) | HTR2CKDM1ALMNATAAR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334893-A1 | Isoxazole Analogs as FXR Agonists and Methods of Use Thereof | ENANTA PHARMACEUTICALS, INC. | 2017-11-23 | — | — | US | disclosed |
| US-20030104945-A1 | 2,4-Diamino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators | AVENTIS CROPSCIENCE GMBH (DE) | 2003-06-05 | — | — | US | disclosed |
| WO-2002092580-A2 | 2,4-DIAMINO-1,3,5-TRIAZINES, METHOD FOR PRODUCING THE SAME AND THE USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS | BAYER CROPSCIENCE GMBH (DE) | 2002-11-21 | — | — | WO | disclosed |
| US-5175183-A | Antiinflammatory agents, respiratory system disorders | ABBOTT LABORATORIES (US) | 1992-12-29 | — | — | US | disclosed |
| WO-1990008545-A1 | LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1990-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334893-A1 | Isoxazole Analogs as FXR Agonists and Methods of Use Thereof | FXR1, SLC10A1, NR1H4 | MAOB 2180/4885HTR2C 1365/4885MAOA 2367/4885 |
| US-20030104945-A1 | 2,4-Diamino-1,3,5-triazines, their preparation, and their use as herbicides and plant growth regulators | DDT, SAT1, DAZAP1 | MAOB 953/4885HTR2C 351/4885MAOA 757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.