Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | HTR2B | P41595 | 2/20 | 0.57 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019855 | 1.00 | HTR2C (0.57) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL25005228 | 0.87 | HTR2C (0.56) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL8098456 | 0.84 | HTR2C (0.54) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL8098198 | 0.84 | HTR2C (0.54) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL8332790 | 0.81 | SLC9A1 (0.56) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL8330687 | 0.79 | SLC9A1 (0.54) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL8332241 | 0.79 | ALOX5 (0.55) | HTR2CHTR2AHTR2BSLC9A1ALOX5 | |
| SCHEMBL7096911 | 0.78 | HTR2C (0.66) | HTR2CHTR2AHTR2BSLC9A1KDM1A | |
| SCHEMBL7865958 | 0.78 | HTR2C (0.66) | HTR2CHTR2AHTR2BSLC9A1KDM1A | |
| SCHEMBL7096910 | 0.78 | HTR2C (0.66) | HTR2CHTR2AHTR2BSLC9A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |