Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22204353 | 0.80 | TRPM8 (0.59) | KMT2AMEN1NPSR1KDM4EPOLB | |
| SCHEMBL10047611 | 0.80 | KMT2A (0.47) | KMT2AALDH1A1LMNATP53GAA | |
| SCHEMBL21295427 | 0.78 | ATM (0.55) | NPSR1PARP10ATMTDP1L3MBTL1 | |
| SCHEMBL19778 | 0.77 | NPSR1 (0.70) | KMT2AALDH1A1GAAMEN1NPSR1 | |
| Methylamine SCHEMBL10655180 | 0.75 | NPSR1 (0.61) | KMT2AALDH1A1GAAMEN1NPSR1 | |
| SCHEMBL14653167 | 0.75 | ATM (0.47) | KMT2AALDH1A1LMNATP53GAA | |
| SCHEMBL28300555 | 0.75 | KMT2A (0.51) | KMT2AALDH1A1LMNATP53GAA | |
| Hydrochloric Acid SCHEMBL5094831 | 0.74 | NPSR1 (0.67) | KMT2AALDH1A1GAAMEN1NPSR1 | |
| Bromide SCHEMBL31210017 | 0.74 | NPSR1 (0.67) | KMT2AALDH1A1GAAMEN1NPSR1 | |
| SCHEMBL4126678 | 0.74 | RXRA (0.46) | KMT2AALDH1A1LMNATP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124807-B2 | Sulfonyl-substituted 6-membered ring derivative | MSD K.K. (JP) | 2012-02-28 | — | — | US | disclosed |