SCHEMBL708660

SCHEMBL708660

c1c[nH]c(Nc2ncc[nH]2)n1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 12/20 0.56
ADRA2C P18825 11/20 0.56
ADRA1D P25100 9/20 0.56
ADRA1A P35348 9/20 0.56
ADRA1B P35368 9/20 0.56
FDPS P14324 1/20 0.48
ALDH1A1 P00352 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MTOR P42345 1/20 0.37
ADK P55263 1/20 0.37
NISCH Q9Y2I1 1/20 0.37
TERT O14746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8310366 0.85 ADRA2A (0.48) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL21556926 0.82
SCHEMBL2981194 0.82
SCHEMBL21067687 0.82 ADRA2A (0.63) ADRA2AADRA2CADRA1DADRA1AADRA1B
SCHEMBL20457775 0.80
SCHEMBL14380959 0.80
SCHEMBL84663 0.80
Bromide SCHEMBL7211375 0.80
Hydrochloric Acid SCHEMBL17162764 0.80
Iodide SCHEMBL11682763 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4649084-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2025-11-19 EP disclosed
EP-4612157-A2 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2025-09-10 EP disclosed
CN-120152954-A Nitrogen-containing heterocyclic compound for organic electroluminescent device 默克专利有限公司 2025-06-13 CN disclosed
WO-2024149694-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-07-18 WO disclosed
WO-2024094592-A2 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-05-10 WO disclosed
US-10077336-B2 Functionalized highly branched melamine-polyamine polymers BASF SE (DE) 2018-09-18 US disclosed
EP-2545123-B1 POLYAMIDES RESISTANT TO HOT AGEING BASF SE (DE) 2018-05-16 EP disclosed
EP-2610248-B1 METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND TEIJIN PHARMA LTD (JP) 2016-06-08 EP disclosed
EP-2143727-B1 Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors ENANTA PHARM INC (US) 2015-01-21 EP disclosed
US-8916714-B2 Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using palladium compound TEIJIN PHARMA LIMITED (JP) 2014-12-23 US disclosed
US-7176208-B2 Prevent reproduction of hepatitis virus ENANTA PHARMACEUTICALS, INC. (US) 2007-02-13 US disclosed
EP-1590442-A3 MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS Enanta Pharmaceuticals, Inc. (US) 2005-11-03 EP disclosed
EP-1590442-A2 MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS Enanta Pharmaceuticals, Inc. (US) 2005-11-02 EP disclosed
US-20050153877-A1 Macrocyclic hepatitis C serine protease inhibitors ENANTA PHARMACEUTICALS, INC. 2005-07-14 US disclosed
US-20040266668-A1 Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors ENANTA PHARMACEUTICALS, INC. 2004-12-30 US disclosed
US-20040180815-A1 Pyridazinonyl macrocyclic hepatitis C serine protease inhibitors NAKAJIMA SUANNE (US) 2004-09-16 US disclosed
WO-2004072243-A2 MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS ENANTA PHARMACEUTICALS, INC. (US) 2004-08-26 WO disclosed
WO-2004012506-A2 ANTIMICROBIAL COMPOUNDS EXEGENICS, INC. (US) 2004-02-12 WO disclosed
WO-2003020969-A2 METHOD FOR MARKING L-NUCLEIC ACIDS NOXXON PHARMA AG (DE) 2003-03-13 WO disclosed
EP-1288309-A1 Methods for labeling L-nucleic acids Noxxon Pharma AG (DE) 2003-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040266668-A1 Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors PRSS1, SPINT2, CTSC ADRA2A 4778/4885ADRA2C 4458/4885ADRA1D 4796/4885
US-20050153877-A1 Macrocyclic hepatitis C serine protease inhibitors PRSS1, SPINT2, TMPRSS4 ADRA2A 4627/4885ADRA2C 3973/4885ADRA1D 4674/4885
US-20040180815-A1 Pyridazinonyl macrocyclic hepatitis C serine protease inhibitors PRSS1, SPINT2, TMPRSS4 ADRA2A 4625/4885ADRA2C 3886/4885ADRA1D 4651/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.