Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 12/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 9/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 9/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 9/20 | 0.48 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL708660 | 0.85 | ADRA2A (0.56) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| SCHEMBL21556926 | 0.80 | — | — | |
| SCHEMBL2981194 | 0.80 | — | — | |
| SCHEMBL18087509 | 0.79 | ADRA2A (0.45) | ADRA2AADRA2CADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL17162764 | 0.78 | — | — | |
| Bromide SCHEMBL7211375 | 0.78 | — | — | |
| SCHEMBL14380959 | 0.78 | — | — | |
| SCHEMBL20457775 | 0.78 | — | — | |
| SCHEMBL84663 | 0.78 | — | — | |
| Iodide SCHEMBL11682763 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0939757-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | Dupont Pharmaceuticals Company (US) | 1999-09-08 | — | — | EP | disclosed |
| WO-1997023480-A1 | NOVEL INTEGRIN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-07-03 | — | — | WO | disclosed |