Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4584399 | 0.81 | TSHR (0.52) | TSHRPPARDGAAPOLBTP53 | |
| SCHEMBL35874 | 0.79 | TSHR (0.44) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL11140616 | 0.78 | PGK1 (0.43) | — | |
| SCHEMBL26483 | 0.74 | TSHR (1.00) | TSHRPPARDACHEGAATP53 | |
| SCHEMBL5961215 | 0.74 | TSHR (1.00) | TSHRPPARDACHEGAATP53 | |
| SCHEMBL21219389 | 0.72 | TSHR (0.58) | TSHRPPARDMAPTMAPK1GAA | |
| SCHEMBL31574613 | 0.72 | TSHR (0.94) | TSHRPPARDACHEGAATP53 | |
| SCHEMBL28492909 | 0.72 | TSHR (0.94) | TSHRPPARDACHEGAATP53 | |
| SCHEMBL11745101 | 0.72 | TSHR (0.94) | TSHRPPARDACHEGAATP53 | |
| SCHEMBL29034374 | 0.72 | TSHR (0.94) | TSHRPPARDACHEMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065045-A1 | Preparation of rigid polyurethane foams having retarded reactivity | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-03 | — | — | US | disclosed |
| US-5688835-A | Preparation of polyurethane rigid foams | BASF ELASTOGRAN GMBH (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5654344-A | Production of rigid to semirigid polyurethane foams having an increased proportion of open cells and reduced shrinkage | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-05 | — | — | US | disclosed |
| US-5578653-A | Preparation of cellular polyurethanes | BASF SCHWARZHEIDE (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5300534-A | Closed-cell foams containing gaseous mixture including vinylfluoroalkane | BASF AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |
| US-5278195-A | Heating, blowing with vinyl fluoroalkane | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-11 | — | — | US | disclosed |
| US-5205956-A | Fluorocarbon blowing agent | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |