SCHEMBL35874

SCHEMBL35874

CCOP(=O)(CN(C(C)O)C(C)O)OCC

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
PPARD Q03181 2/20 0.43
GAA P10253 2/20 0.40
MEN1 O00255 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Monoethanolamine SCHEMBL18530680 0.89 PPARD (0.44) TSHRPPARDGAAMEN1CYP2C9
SCHEMBL1477184 0.82 PPARD (0.45) TSHRPPARDGAATDP1TP53
SCHEMBL14775210 0.79 TSHR (0.44) TSHRPPARDGAAMEN1CYP2C9
SCHEMBL7086754 0.79 TSHR (0.56) TSHRPPARDGAAMEN1CYP2C9
SCHEMBL8463197 0.76 GAA (0.45) TSHRPPARDGAAMEN1CYP2C9
SCHEMBL4584399 0.73 TSHR (0.52) TSHRPPARDGAAMEN1KMT2A
SCHEMBL6750640 0.71 TSHR (0.50) TSHRPPARDGAATDP1TP53
SCHEMBL9442588 0.70 TSHR (0.55) TSHRPPARDGAAMEN1CYP2C9
SCHEMBL1420968 0.70 FDPS (0.37) TDP1MAPK1
SCHEMBL6990163 0.70 TSHR (0.40) TSHRPPARDGAATDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 429 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6734217-B1 OBTAINED BY REACTING MODIFIED TDI WITH PHD OR PIPA POLYMER POLYOLS BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-4442041-A Method for preparation of N-phosphonomethylglycine STAUFFER CHEMICAL COMPANY (US) 1984-04-10 US claimed
WO-2024132976-A1 POLYESTER POLYOL BASED ON POLYBUTYLENE TEREPHTHALATE BASF SE (DE) 2024-06-27 WO disclosed
WO-2024115432-A1 WATER BLOWN ENVIRONMENTALLY FRIENDLY HIGH YIELD SPRAY POLYURETHANE FOAM BASF SE (DE) 2024-06-06 WO disclosed
US-20240174789-A1 PROCESS FOR PRODUCING OPEN-CELL RIGID POLYURETHANE FOAMS BASF SE (DE) 2024-05-30 US disclosed
EP-4373873-A1 RIGID POLYURETHANE FOAMS BASED ON FATTY-ACID-MODIFIED POLYETHER POLYOLS AND CROSSLINKING POLYESTER POLYOLS BASF SE (DE) 2024-05-29 EP disclosed
WO-2024096542-A1 POLYURETHANE FOAM, METHOD FOR PRODUCING SAME, AND INSULATION MATERIAL COMPRISING SAME 케이피엑스케미칼 주식회사 2024-05-10 WO disclosed
WO-2024096541-A1 POLYESTER POLYOL, METHOD FOR PRODUCING SAME, METHOD FOR PRODUCING POLYURETHANE THEREBY, POLYURETHANE, AND INSULATION MATERIAL 케이피엑스케미칼 주식회사 2024-05-10 WO disclosed
US-11970594-B2 2024-04-30 US disclosed
US-20240026060-A1 POLYESTER POLYOL AND POLYURETHANE PREPARED THEREFROM LOTTE CHEMICAL CORPORATION (KR) 2024-01-25 US disclosed
EP-4305086-A1 PROCESS FOR PRODUCING OPEN-CELL RIGID POLYURETHANE FOAMS BASF SE (DE) 2024-01-17 EP disclosed
US-4804500-A Amine dealkylation process MONSANTO COMPANY (US) 1989-02-14 US disclosed
EP-0297369-A2 Process for the preparation of N-phosphonomethylglycine HOECHST AKTIENGESELLSCHAFT (DE) 1989-01-04 EP disclosed
US-4442041-A Method for preparation of N-phosphonomethylglycine STAUFFER CHEMICAL COMPANY (US) 1984-04-10 US disclosed
US-4442041-A Method for preparation of N-phosphonomethylglycine STAUFFER CHEMICAL COMPANY (US) 1984-04-10 US disclosed
US-4247654-A Alkoxylated formose polyols and their use in polyurethane plastics BAYER AKTIENGESELLSCHAFT (DE) 1981-01-27 US disclosed
US-4172858-A Flame-resistant polymer compositions CIBA-GEIGY AG (CH) 1979-10-30 US disclosed
US-4113671-A Carbamate-phosphonates as flame-proofing agents in polyurethane foam SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1978-09-12 US disclosed
US-4077964-A FLAME RETARDANTS FOR POLYURETHANE FOAMS SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1978-03-07 US disclosed
US-4022757-A Dicarbamic acid diesters containing phosphorus BAYER AKTIENGESELLSCHAFT (DT) 1977-05-10 US disclosed