Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951229 | 0.80 | ALDH1A1 (0.43) | LMNATSHRALDH1A1ATM | |
| SCHEMBL1057947 | 0.80 | ALDH1A1 (0.43) | TSHRALDH1A1MEN1KMT2AATM | |
| SCHEMBL7082490 | 0.79 | FFAR4 (0.50) | LMNAFFAR4LTB4RTSHRLTB4R2 | |
| SCHEMBL612449 | 0.78 | FFAR4 (0.51) | LMNAFFAR4ALDH1A1MEN1KMT2A | |
| SCHEMBL2353503 | 0.77 | ALDH1A1 (0.47) | LMNATSHRALDH1A1MEN1KMT2A | |
| SCHEMBL5319605 | 0.77 | LMNA (0.83) | LMNAFFAR4TSHRALDH1A1 | |
| SCHEMBL29787159 | 0.77 | TRPV1 (0.44) | LMNAFFAR4TSHRALDH1A1 | |
| SCHEMBL6112724 | 0.77 | PPARA (0.52) | LMNAFFAR4LTB4RLTB4R2ALDH1A1 | |
| SCHEMBL95873 | 0.76 | ALDH1A1 (0.53) | TSHRALDH1A1MEN1KMT2AATM | |
| SCHEMBL6112796 | 0.75 | PPARA (0.55) | FFAR4LTB4RLTB4R2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | claimed |
| WO-2003068806-A1 | SOLID PHASE PEPTIDE SYNTHESIS ON SILICA | JOHNSON MATTHEY PLC (GB) | 2003-08-21 | — | — | WO | disclosed |