Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7087064 | 0.95 | MEN1 (0.42) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL7508013 | 0.94 | MEN1 (0.45) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL10061204 | 0.79 | KMT2A (0.38) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL20334220 | 0.74 | MAPK10 (0.66) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL12658889 | 0.72 | TOP2B (0.59) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL20710632 | 0.72 | TOP2B (0.62) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL20334300 | 0.72 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL1760731 | 0.71 | MEN1 (0.46) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL23787768 | 0.71 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTPOLB | |
| SCHEMBL11310247 | 0.71 | MEN1 (0.54) | MEN1KMT2ASMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073853-A1 | Cationic aminoanthraquinones, their use for dyeing keratinous fibers, dyeing compositions containing them and methods of dyeing | L'OREAL S.A. | 2003-04-17 | — | — | US | claimed |
| US-6437149-B1 | AT LEAST ONE CATIONIC CHARGE IS DELOCALIZED ON A 5-MEMBERED UNSATURATED POLYNITROGEN RING; DIRECT HAIR DYES, SOLUBILITY, COLORFAST | L'OREAL S.A. (FR) | 2002-08-20 | — | — | US | claimed |
| EP-1006154-B1 | Cationic aminoanthraquinones, use thereof for the dyeing of keratinous fibres, dyeing compositions containing them and dyeing processes | OREAL (FR) | 2002-04-17 | — | — | EP | claimed |
| US-6645259-B2 | Cationic direct hair dye | L'OREAL S.A. (FR) | 2003-11-11 | — | — | US | disclosed |
| US-20030073853-A1 | Cationic aminoanthraquinones, their use for dyeing keratinous fibers, dyeing compositions containing them and methods of dyeing | L'OREAL S.A. | 2003-04-17 | — | — | US | disclosed |
| US-6437149-B1 | AT LEAST ONE CATIONIC CHARGE IS DELOCALIZED ON A 5-MEMBERED UNSATURATED POLYNITROGEN RING; DIRECT HAIR DYES, SOLUBILITY, COLORFAST | L'OREAL S.A. (FR) | 2002-08-20 | — | — | US | disclosed |