Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.62 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | BLM | P54132 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | NSD2 | O96028 | 3/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | RECQL | P46063 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12658889 | 0.94 | TOP2B (0.59) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL375450 | 0.92 | TOP2B (0.71) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL15278008 | 0.92 | TOP2B (0.72) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL29670831 | 0.91 | TOP2B (0.70) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL23404 | 0.91 | TOP2B (0.70) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL29374910 | 0.91 | TOP2B (0.70) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL455300 | 0.89 | TOP2B (0.72) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL9883948 | 0.88 | TOP2B (0.62) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL15271588 | 0.87 | TOP2B (0.73) | TOP2BCYP19A1MEN1KMT2ABLM | |
| SCHEMBL23787768 | 0.87 | MEN1 (0.54) | TOP2BCYP19A1MEN1KMT2ABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190038534-A1 | COMPOSITION FOR COLOURING HAIR | BEAUTY & BUSINESS S.P.A. (IT) | 2019-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190038534-A1 | COMPOSITION FOR COLOURING HAIR | TYR, CUTA, COX5B | TOP2B 759/4885CYP19A1 537/4885MEN1 2221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.