Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7538126 | 0.91 | TSHR (0.41) | TSHRHCAR2ATMMEN1KMT2A | |
| SCHEMBL384901 | 0.86 | TSHR (0.42) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL1813100 | 0.82 | TSHR (0.47) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL1813102 | 0.81 | TSHR (0.46) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL3462874 | 0.81 | TSHR (0.46) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL275851 | 0.80 | TSHR (0.40) | TSHRMEN1KMT2ACTSKHSD17B10 | |
| SCHEMBL12904846 | 0.80 | TSHR (0.40) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL12263773 | 0.79 | TSHR (0.48) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL16244087 | 0.79 | TSHR (0.45) | TSHRMEN1KMT2ACTSKPOLB | |
| SCHEMBL3462896 | 0.79 | TSHR (0.45) | TSHRMEN1KMT2ACTSKPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0867443-B1 | Hydrolyzable and polymerizable oxetanesilanes | IVOCLAR VIVADENT AG (LI) | 2003-08-06 | — | — | EP | disclosed |
| EP-0867443-A2 | Hydrolyzable and polymerizable oxetanesilanes | IVOCLAR AG (LI) | 1998-09-30 | — | — | EP | disclosed |