Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6777739 | 0.73 | ADRA1D (0.59) | ADRA1DADRA1APIK3CDKMT2ACYP1A2 | |
| SCHEMBL6779493 | 0.71 | ADRA1A (0.48) | ADRA1DADRA1APIK3CDKMT2AMEN1 | |
| SCHEMBL22398815 | 0.70 | TP53 (0.48) | PIK3CDKMT2AMEN1PKMCYP1A2 | |
| SCHEMBL1576503 | 0.70 | TP53 (0.48) | PIK3CDKMT2AMEN1PKMCYP1A2 | |
| SCHEMBL6778184 | 0.68 | ADRA1D (0.37) | ADRA1DADRA1APIK3CDKDM4EL3MBTL1 | |
| SCHEMBL9011436 | 0.67 | TP53 (0.45) | ADRA1DADRA1APIK3CDKMT2AMEN1 | |
| SCHEMBL6776019 | 0.66 | CHRM1 (0.64) | ADRA1DADRA1ACHRM1 | |
| Oxirane SCHEMBL10529044 | 0.66 | TP53 (0.44) | PIK3CDKMT2AMEN1PKMCYP1A2 | |
| SCHEMBL22442274 | 0.65 | CHRM2 (0.39) | PIK3CDKMT2AMEN1PKMCYP1A2 | |
| SCHEMBL6784178 | 0.64 | CA12 (0.55) | ADRA1DADRA1AKMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114491-A1 | Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-19 | — | — | US | claimed |
| US-20030114491-A1 | Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114491-A1 | Pyrrolidinone derivatives, their preparation and pharmaceutical composition comprising the same | CHRM1, CHRNA5, CHRNA7 | ADRA1D 26/4885ADRA1A 24/4885PIK3CD 530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.