Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CCR2 | P41597 | 2/20 | 0.52 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.46 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476665 | 0.87 | CCR2 (0.60) | KDM4ESMN1; SMN2CCR2KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9085791 | 0.86 | ALDH1A1 (0.59) | KDM4ESMN1; SMN2CCR2KMT2AMEN1 | |
| SCHEMBL9085776 | 0.86 | KDM4E (0.55) | KDM4ESMN1; SMN2CCR2KMT2AMEN1 | |
| SCHEMBL10629278 | 0.82 | KMT2A (0.71) | KDM4ESMN1; SMN2F10KMT2AMEN1 | |
| SCHEMBL27539310 | 0.82 | KMT2A (0.61) | SMN1; SMN2CCR2PLA2G10F10KMT2A | |
| SCHEMBL1757508 | 0.81 | KDM4E (0.59) | KDM4ESMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL13738783 | 0.80 | CCR2 (0.58) | CCR2PLA2G10F10KMT2AMEN1 | |
| SCHEMBL30044340 | 0.80 | CCR2 (0.58) | CCR2PLA2G10F10KMT2AMEN1 | |
| SCHEMBL20609049 | 0.80 | HDAC3 (0.53) | KDM4ESMN1; SMN2CCR2PLA2G10F10 | |
| SCHEMBL30622530 | 0.80 | HDAC3 (0.53) | KDM4ESMN1; SMN2CCR2PLA2G10F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |