Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SERPINE1 | P05121 | 12/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142564 | 0.78 | SERPINE1 (0.66) | MAPTHTTL3MBTL1LMNASERPINE1 | |
| SCHEMBL7087727 | 0.76 | SERPINE1 (1.00) | MAPTHTTL3MBTL1LMNASERPINE1 | |
| SCHEMBL101570 | 0.75 | ALDH1A1 (0.69) | MAPTHTTL3MBTL1LMNAMEN1 | |
| SCHEMBL30434695 | 0.74 | POLB (0.58) | MAPTHTTL3MBTL1MEN1KMT2A | |
| SCHEMBL9564464 | 0.74 | POLB (0.58) | MAPTHTTL3MBTL1MEN1KMT2A | |
| SCHEMBL5329963 | 0.74 | MAPT (0.64) | MAPTHTTL3MBTL1LMNASERPINE1 | |
| SCHEMBL7091041 | 0.74 | LMNA (0.70) | MAPTHTTL3MBTL1LMNASERPINE1 | |
| SCHEMBL7450080 | 0.73 | MAPT (0.66) | MAPTHTTL3MBTL1LMNAMEN1 | |
| SCHEMBL28226906 | 0.73 | ALDH1A1 (0.77) | MAPTHTTL3MBTL1LMNAMEN1 | |
| SCHEMBL29074136 | 0.72 | POLB (0.55) | MAPTL3MBTL1LMNAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |