Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 13/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088384 | 0.92 | SERPINE1 (0.56) | SERPINE1ENPP2SCN9ATP53TSHR | |
| SCHEMBL7089570 | 0.88 | SERPINE1 (0.61) | SERPINE1TP53TSHR | |
| SCHEMBL7089626 | 0.85 | SERPINE1 (0.51) | SERPINE1ENPP2 | |
| SCHEMBL7088122 | 0.81 | SERPINE1 (0.59) | SERPINE1TSHR | |
| SCHEMBL7087862 | 0.80 | SERPINE1 (0.58) | SERPINE1ENPP2 | |
| SCHEMBL7091878 | 0.78 | SERPINE1 (0.56) | SERPINE1ENPP2 | |
| SCHEMBL7163081 | 0.75 | SERPINE1 (0.54) | SERPINE1ENPP2SCN9A | |
| SCHEMBL7084122 | 0.75 | SERPINE1 (0.53) | SERPINE1ENPP2 | |
| SCHEMBL7085685 | 0.73 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7084544 | 0.73 | SERPINE1 (0.59) | SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |