Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31533329 | 1.00 | KDM4E (0.64) | KDM4EGLAPOLBATMKMT2A | |
| SCHEMBL6318031 | 0.93 | KDM4E (0.72) | KDM4EGLAPOLBATMKMT2A | |
| SCHEMBL29365352 | 0.88 | ALDH1A1 (0.67) | KDM4EPOLBKMT2AMAPTALOX15 | |
| SCHEMBL1170114 | 0.88 | ALDH1A1 (0.67) | KDM4EPOLBKMT2AMAPTALOX15 | |
| SCHEMBL7034926 | 0.84 | MAPT (0.74) | KDM4EGLAPOLBATMKMT2A | |
| SCHEMBL29171764 | 0.83 | HIF1A (0.60) | KDM4EGLAPOLBATMKMT2A | |
| SCHEMBL31629989 | 0.83 | KDM4E (0.59) | KDM4EGLAPOLBATMKMT2A | |
| SCHEMBL2707530 | 0.81 | KDM4E (0.66) | KDM4EGLAPOLBATMKMT2A | |
| SCHEMBL1903514 | 0.81 | KDM4E (0.70) | KDM4EGLAPOLBATMKMT2A | |
| Methyl Salicylate SCHEMBL4644673 | 0.80 | LMNA (0.63) | KDM4EGLAPOLBATMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996655-B1 | THIXOTROPIC TWO-COMPONENT POLYURETHANE SYSTEMS | SIKA GMBH (DE) | 2003-08-06 | — | — | EP | claimed |
| EP-0996655-A1 | THIXOTROPIC TWO-COMPONENT POLYURETHANE SYSTEMS | Sika Chemie GmbH (DE) | 2000-05-03 | — | — | EP | claimed |
| WO-1999002578-A1 | THIXOTROPIC TWO-COMPONENT POLYURETHANE SYSTEMS | SIKA CHEMIE GMBH (DE) | 1999-01-21 | — | — | WO | claimed |
| EP-0996655-B1 | THIXOTROPIC TWO-COMPONENT POLYURETHANE SYSTEMS | SIKA GMBH (DE) | 2003-08-06 | — | — | EP | disclosed |
| EP-0996655-A1 | THIXOTROPIC TWO-COMPONENT POLYURETHANE SYSTEMS | Sika Chemie GmbH (DE) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999002578-A1 | THIXOTROPIC TWO-COMPONENT POLYURETHANE SYSTEMS | SIKA CHEMIE GMBH (DE) | 1999-01-21 | — | — | WO | disclosed |
| EP-0509271-A2 | Siloxi-Polytetrahydrofuran | BASF Aktiengesellschaft (DE) | 1992-10-21 | — | — | EP | disclosed |