SCHEMBL7088060

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15209661	0.82	GSK3B (0.59)	GSK3BGRM5KMT2AALDH1A1CES2
	SCHEMBL7084885	0.79	GSK3B (0.54)	GSK3BGRM5SIRT2KMT2AMEN1
	SCHEMBL7090904	0.78	PARP1 (0.50)	KMT2AMEN1MAPTSMN1; SMN2CES2
	SCHEMBL7090547	0.76	CES2 (0.65)	ALDH1A1MAPTMAPK1CES2CES1
	SCHEMBL5859663	0.76	PLK1 (0.61)	KMT2AMEN1CYP1A2CYP3A4CYP2C9
	SCHEMBL9342487	0.75	P4HB (0.72)	P4HB
	SCHEMBL9342479	0.75	P4HB (0.72)	P4HB
	SCHEMBL11786369	0.75	GSK3B (0.59)	GSK3BGRM5KMT2AMEN1ALDH1A1
	SCHEMBL11757430	0.74	CA1 (0.50)	GSK3BSIRT2KMT2AMEN1CYP1A2
	SCHEMBL39137	0.73	GSK3B (0.61)	GSK3BGRM5KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.