Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.56 |
| ▸ | FNTB | P49356 | 7/20 | 0.56 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372174 | 0.82 | HSD17B10 (0.72) | FNTAFNTBHSD17B10CYP3A4 | |
| SCHEMBL7209358 | 0.82 | HSD17B10 (0.72) | FNTAFNTBHSD17B10CYP3A4 | |
| SCHEMBL6171808 | 0.79 | FNTA (0.68) | FNTAFNTBCYP3A4 | |
| SCHEMBL8171779 | 0.78 | FNTA (0.55) | FNTAFNTBHSD17B10 | |
| SCHEMBL6010441 | 0.78 | FNTA (0.57) | FNTAFNTBHSD17B10 | |
| SCHEMBL5658195 | 0.78 | FNTA (0.60) | FNTAFNTBCYP3A4 | |
| Hydrochloric Acid SCHEMBL5657991 | 0.77 | FNTA (0.59) | FNTAFNTBCYP3A4 | |
| SCHEMBL5655930 | 0.77 | FNTA (0.68) | FNTAFNTBCYP3A4 | |
| SCHEMBL5656557 | 0.77 | FNTA (0.71) | FNTAFNTBCYP3A4 | |
| SCHEMBL5658384 | 0.77 | FNTA (0.71) | FNTAFNTBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199544-A1 | Farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2003-10-23 | — | — | US | disclosed |
| US-20030199542-A1 | Farnesyltransferase inhibitors | WEINSTOCK, STEVEN F. | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199542-A1 | Farnesyltransferase inhibitors | FNTA, FNTB, LCAT | FNTA 1/4885FNTB 2/4885CDC7 1030/4885 |
| US-20030199544-A1 | Farnesyltransferase inhibitors | FNTA, FNTB, LCAT | FNTA 1/4885FNTB 2/4885CDC7 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.