SCHEMBL708886

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL711273	0.93	GPR34 (0.40)	GPR34PDE4BC5AR1PDGFRBPDGFRA
	SCHEMBL10206516	0.93	MCL1 (0.41)	PDE4BPDGFRBPDGFRAPPARDMAOB
	SCHEMBL711592	0.92	MCL1 (0.40)	GPR34PDE4BPDGFRBPDGFRAMCL1
	SCHEMBL720812	0.90	GPR34 (0.41)	GPR34PPARDMAOB
	SCHEMBL711177	0.88	PRMT5 (0.42)	PDE4BPDGFRBPDGFRA
	SCHEMBL710136	0.88	MAPT (0.43)	PDE4BC5AR1PDGFRBPDGFRAMAOB
	Trifluoroacetic Acid SCHEMBL711184	0.87	MCL1 (0.41)	GPR34FFAR1PPARDMCL1DHODH
	SCHEMBL713544	0.87	FFAR1 (0.40)	PDGFRBPDGFRAFFAR1PPARDKIT
	SCHEMBL719831	0.87	MAP4K4 (0.43)	GPR34C5AR1MCL1DHODH
	SCHEMBL712000	0.86	PRMT5 (0.38)	PDE4BPDGFRBPDGFRAFFAR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.