Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | PRCP | P42785 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091260 | 0.81 | HDAC3 (0.47) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL26955949 | 0.81 | FFAR2 (0.68) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL1978851 | 0.79 | HDAC4 (0.68) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL25460815 | 0.78 | FFAR2 (1.00) | FFAR2MEN1KMT2A | |
| SCHEMBL10949851 | 0.78 | FFAR2 (1.00) | FFAR2MEN1KMT2A | |
| SCHEMBL13789274 | 0.77 | FFAR2 (0.62) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL3736159 | 0.76 | FFAR2 (0.61) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL20290805 | 0.76 | FFAR2 (0.61) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 | |
| SCHEMBL11949354 | 0.72 | ADRB2 (0.62) | FFAR2HDAC4HDAC7HDAC5SLC6A4 | |
| SCHEMBL21430159 | 0.71 | FFAR2 (0.56) | FFAR2ALDH1A1HDAC4HDAC7HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322599-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-02 | — | — | EP | disclosed |
| WO-2001096283-A9 | HIV INTEGRASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2002-10-17 | — | — | WO | disclosed |
| WO-2001096283-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |