Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089299 | 0.77 | KDM4E (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7591578 | 0.75 | MAPT (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11766616 | 0.74 | MAPT (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7094248 | 0.73 | ALDH1A1 (0.54) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29050814 | 0.71 | TP53 (0.45) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28242757 | 0.71 | MAPT (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17743517 | 0.71 | CYP2C9 (0.37) | ALDH1A1MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL25944761 | 0.70 | ALDH1A1 (0.51) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL9094641 | 0.70 | ALDH1A1 (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7592197 | 0.70 | ALDH1A1 (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084662-A2 | COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |