Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089183 | 0.77 | HTR3E (0.43) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL21113673 | 0.76 | KMT2A (0.49) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL11762909 | 0.76 | MEN1 (0.45) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL21113690 | 0.75 | KMT2A (0.36) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL17743517 | 0.74 | CYP2C9 (0.37) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL5707009 | 0.74 | CYP2C9 (0.37) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL21192720 | 0.73 | HTR3E (0.51) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL21192724 | 0.73 | HTR3E (0.51) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 | |
| SCHEMBL28864118 | 0.72 | L3MBTL1 (0.46) | KDM4ESMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL28242741 | 0.72 | GAA (0.45) | KDM4ESMN1; SMN2HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084662-A2 | COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |