Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | PLK4 | O00444 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089445 | 1.00 | HDAC3 (0.48) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7092254 | 0.92 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7136710 | 0.92 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7092561 | 0.92 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7089006 | 0.91 | HDAC3 (0.45) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7092305 | 0.91 | FOXO1 (0.46) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL13542841 | 0.90 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7095011 | 0.88 | HDAC3 (0.43) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL6659321 | 0.88 | HDAC3 (0.45) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL6659312 | 0.88 | HDAC3 (0.45) | HDAC3NCOR2HDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | claimed |
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | disclosed |