Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOXO1 | Q12778 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089449 | 0.91 | HDAC3 (0.48) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7089445 | 0.91 | HDAC3 (0.48) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7092254 | 0.86 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL13542841 | 0.86 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7089006 | 0.85 | HDAC3 (0.45) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL13542838 | 0.83 | THRB (0.49) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7092561 | 0.83 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7136710 | 0.83 | HDAC3 (0.44) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7095011 | 0.82 | HDAC3 (0.43) | HDAC3NCOR2HDAC1HDAC6HDAC2 | |
| SCHEMBL7089754 | 0.80 | HDAC3 (0.47) | HDAC3NCOR2HDAC1HDAC6HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087127-A2 | ANTIMICROBIAL COMPOUNDS AGAINST STAPHYLOCOCCI, MYCOBACTERIA, AND OTHER INFECTIOUS AGENTS | EXEGENICS INC. (US) | 2003-10-23 | — | — | WO | disclosed |