Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 12/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091114 | 0.87 | SERPINE1 (0.77) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7087633 | 0.80 | SERPINE1 (0.78) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7085685 | 0.78 | SERPINE1 (1.00) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7088258 | 0.77 | SERPINE1 (0.65) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7085804 | 0.75 | SERPINE1 (0.88) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL30883140 | 0.73 | SERPINE1 (0.61) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7087872 | 0.73 | SERPINE1 (1.00) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7091901 | 0.73 | SERPINE1 (0.71) | SERPINE1MAPTHTTLMNAL3MBTL1 | |
| SCHEMBL7088218 | 0.72 | SERPINE1 (1.00) | SERPINE1MEN1KMT2AMAPTHTT | |
| SCHEMBL7087727 | 0.72 | SERPINE1 (1.00) | SERPINE1MEN1KMT2AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |