Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2082260 | 0.82 | GABRA1 (0.39) | TSHRALDH1A1TRIM24TRIM33NPC1 | |
| SCHEMBL4030522 | 0.81 | TAAR1 (0.45) | TSHRNISCHNPC1RAB9ACYP1A2 | |
| SCHEMBL5574440 | 0.80 | TSHR (0.43) | TSHRALDH1A1RAB9ACYP1A2CYP2C19 | |
| SCHEMBL30415398 | 0.79 | TRIM24 (0.32) | ALDH1A1TRIM24TRIM33MEN1KMT2A | |
| SCHEMBL19779547 | 0.79 | TSHR (0.43) | TSHRNISCHHTTALDH1A1NPC1 | |
| SCHEMBL23641465 | 0.78 | TRIM24 (0.33) | ALDH1A1TRIM24TRIM33 | |
| SCHEMBL4035437 | 0.77 | TRPA1 (0.36) | ALDH1A1NPC1RAB9ACYP1A2CYP2D6 | |
| SCHEMBL21536891 | 0.77 | TSHR (0.47) | TSHRNISCHHTTALDH1A1NPC1 | |
| SCHEMBL1494290 | 0.77 | TSHR (0.47) | TSHRNISCHHTTALDH1A1NPC1 | |
| SCHEMBL12891652 | 0.77 | TSHR (0.47) | TSHRNISCHHTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084662-A2 | COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |