Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Drometrizole SCHEMBL2728302 | 0.84 | NPC1 (0.78) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Drometrizole SCHEMBL17232890 | 0.84 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1263997 | 0.83 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Oxybenzone SCHEMBL21694096 | 0.81 | LMNA (0.62) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11594004 | 0.78 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL1262808 | 0.78 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11339738 | 0.77 | NPC1 (0.74) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| Drometrizole SCHEMBL25341481 | 0.76 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14324606 | 0.75 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL14594216 | 0.75 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080364-A1 | SECURITY PAPER AND OTHER SECURITY ITEMS | LANDQART (CH) | 2003-10-02 | — | — | WO | disclosed |
| EP-1348575-A1 | Security paper and other security items | Landqart (CH) | 2003-10-01 | — | — | EP | disclosed |