Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.58 |
| ▸ | RAB9A | P51151 | 10/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1262808 | 0.91 | NPC1 (0.54) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1263238 | 0.85 | NPC1 (0.62) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL7089753 | 0.83 | NPC1 (0.59) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1264052 | 0.83 | BCL2 (0.49) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1263980 | 0.83 | NPC1 (0.42) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL14594216 | 0.82 | NPC1 (0.48) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL9418498 | 0.82 | NPC1 (0.43) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1263991 | 0.81 | NPC1 (0.40) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1264285 | 0.81 | NPC1 (0.58) | NPC1RAB9APOLBLMNASMN1; SMN2 | |
| SCHEMBL1262810 | 0.81 | NPC1 (0.58) | NPC1RAB9APOLBLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332013-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | Chang, Chia-Hu (US) | 2011-06-15 | — | — | EP | claimed |
| US-7847103-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-12-07 | — | — | US | claimed |
| US-20100086500-A1 | Ultraviolet light absorbing ketones of 2-(2-Hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-04-08 | — | — | US | claimed |
| WO-2010039229-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | CHANG CHIA-HU (US) | 2010-04-08 | — | — | WO | claimed |
| JP-11310576-A | — | — | None | — | — | JP | disclosed |
| US-20120329885-A1 | Ultraviolet light absorbing compounds based on benzyl substituted 2-(2- hydroxyphenyl) benzotriazoles | CHANG CHIA-HU (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329885-A1 | Ultraviolet light absorbing compounds based on benzyl substituted 2-(2- hydroxyphenyl) benzotriazoles | CHANG CHIA-HU (US) | 2012-12-27 | — | — | US | disclosed |
| US-20120329885-A1 | Ultraviolet light absorbing compounds based on benzyl substituted 2-(2- hydroxyphenyl) benzotriazoles | CHANG CHIA-HU (US) | 2012-12-27 | — | — | US | disclosed |
| US-8163934-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163934-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU (US) | 2012-04-24 | — | — | US | disclosed |
| US-8163934-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU (US) | 2012-04-24 | — | — | US | disclosed |
| EP-2332013-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | Chang, Chia-Hu (US) | 2011-06-15 | — | — | EP | disclosed |
| US-20110038816-A1 | Ultraviolet light absorbing ketones of 2-(2-hydroxyhenyl) benzotriazole | CHANG CHIA-HU | 2011-02-17 | — | — | US | disclosed |
| US-7847103-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-12-07 | — | — | US | disclosed |
| US-7847103-B2 | Ultraviolet light absorbing ketones of 2-(2-hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-12-07 | — | — | US | disclosed |
| US-20100086500-A1 | Ultraviolet light absorbing ketones of 2-(2-Hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-04-08 | — | — | US | disclosed |
| US-20100086500-A1 | Ultraviolet light absorbing ketones of 2-(2-Hydroxyphenyl) benzotriazole | CHANG CHIA-HU | 2010-04-08 | — | — | US | disclosed |
| WO-2010039229-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | CHANG CHIA-HU (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039229-A1 | ULTRAVIOLET LIGHT ABSORBING KETONES OF 2-(2-HYDROXYPHENYL) BENZOTRIAZOLE | CHANG CHIA-HU (US) | 2010-04-08 | — | — | WO | disclosed |
| JP-H11310576-A | BENZOTRIAZOLE DERIVATIVE, ITS PRODUCTION, AND ULTRAVIOLET LIGHT ABSORBENT AND TREATING AGENT FOR FIBER MATERIAL CONTAINING THE DERIVATIVE | NICCA CHEM CO LTD | 1999-11-09 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110038816-A1 | Ultraviolet light absorbing ketones of 2-(2-hydroxyhenyl) benzotriazole | HCRTR2, HCRTR1, POLL | NPC1 2019/4885RAB9A 4833/4885POLB 1185/4885 |
| US-20120329885-A1 | Ultraviolet light absorbing compounds based on benzyl substituted 2-(2- hydroxyphenyl) benzotriazoles | AHR, ARNT, BCAT1 | NPC1 3659/4885RAB9A 4167/4885POLB 1373/4885 |
| US-20100086500-A1 | Ultraviolet light absorbing ketones of 2-(2-Hydroxyphenyl) benzotriazole | HCRTR2, HCRTR1, PAH | NPC1 1975/4885RAB9A 4829/4885POLB 1169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.