Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089807 | 0.84 | ABCB11 (0.40) | MAPK1TSHRSMN1; SMN2KDM4EHPGD | |
| SCHEMBL7086850 | 0.83 | TSHR (0.47) | MAPK1TSHRSMN1; SMN2LMNATP53 | |
| SCHEMBL3671328 | 0.78 | MAPK1 (0.83) | MAPK1TSHRHIF1ASMN1; SMN2KDM4E | |
| SCHEMBL7089770 | 0.78 | CYP2C9 (0.43) | MAPK1TSHRGAALMNAHPGD | |
| SCHEMBL14595237 | 0.76 | TSHR (0.59) | MAPK1TSHRHIF1ASMN1; SMN2KDM4E | |
| SCHEMBL7089758 | 0.74 | CYP2C9 (0.41) | TSHRLMNA | |
| SCHEMBL7086825 | 0.74 | CYP1A2 (0.53) | MAPK1TSHRSMN1; SMN2KDM4ELMNA | |
| SCHEMBL7087004 | 0.74 | BACE1 (0.41) | MAPK1TSHRLMNA | |
| SCHEMBL7084185 | 0.74 | CYP2C9 (0.41) | MAPK1TSHRLMNA | |
| SCHEMBL7086556 | 0.72 | HIF1A (0.64) | MAPK1TSHRHIF1ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030149219-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | BORIACK CLINTON J (US) | 2003-08-07 | — | — | US | claimed |
| US-6534621-B2 | Epoxidizing an alpha-halohydrin intermediate produced from an in situ halide substitution-deesterification of an alpha-hydroxy ester derivative | DOW GLOBAL TECHNOLOGIES INC. | 2003-03-18 | — | — | US | claimed |
| US-20020045707-A1 | Process for manufacturing a hydroxyester derivative intermediate and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2002-04-18 | — | — | US | claimed |