Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | JUN | P05412 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663567 | 1.00 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL708982 | 1.00 | NPC1 (1.00) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL709965 | 0.89 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL709964 | 0.89 | NPC1 (0.80) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL710451 | 0.87 | NPC1 (0.77) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL710452 | 0.87 | NPC1 (0.77) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL11180576 | 0.85 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL30596295 | 0.84 | NPC1 (0.72) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| Pyridine SCHEMBL27723525 | 0.84 | MEN1 (0.72) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691623 | 0.83 | CYP11B1 (0.86) | NPC1RAB9AMEN1KMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114716463-B | Light response complex and preparation method and application thereof | 淮阴师范学院 | 2024-02-06 | — | — | CN | claimed |
| CN-115403598-A | Photosensitive semiconductor material and preparation method and application thereof | 淮阴师范学院 | 2022-11-29 | — | — | CN | claimed |
| CN-114716463-A | Photoresponse complex and preparation method and application thereof | 淮阴师范学院 | 2022-07-08 | — | — | CN | claimed |
| CN-114716463-B | Light response complex and preparation method and application thereof | 淮阴师范学院 | 2024-02-06 | — | — | CN | disclosed |
| CN-115403598-A | Photosensitive semiconductor material and preparation method and application thereof | 淮阴师范学院 | 2022-11-29 | — | — | CN | disclosed |
| CN-114716463-A | Photoresponse complex and preparation method and application thereof | 淮阴师范学院 | 2022-07-08 | — | — | CN | disclosed |
| US-8124625-B2 | enhancing the expression of apoAI; prevention or therapy of dislipidemia | SHIONOGI & CO., LTD. (JP) | 2012-02-28 | — | — | US | disclosed |
| US-8053445-B2 | Utilities of olefin derivatives | SHIONOGI & CO., LTD. (JP) | 2011-11-08 | — | — | US | disclosed |
| US-20090036457-A1 | Utilities of olefin derivatives | YAMAMORI TERUO | 2009-02-05 | — | — | US | disclosed |
| US-20040242615-A1 | Utilities of olefin derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242615-A1 | Utilities of olefin derivatives | APOL1, NR1H2, APOB | NPC1 19/4885RAB9A 4723/4885MEN1 3997/4885 |
| US-20090036457-A1 | Utilities of olefin derivatives | APOL1, APOB, NR1H2 | NPC1 48/4885RAB9A 4606/4885MEN1 3163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.